{"product_id":"krosfloimplantmembrane","title":"KrosFlo Implant Membranes","description":"\u003ch4 class=\"Header\"\u003eKrosFlo\u003csup\u003e®\u003c\/sup\u003e\u003cspan\u003e \u003c\/span\u003eImplant Membrane for Drug Discovery \u0026amp; Development\u003c\/h4\u003e\n\u003cp class=\"Header\"\u003eProprietary KrosFlo hollow fiber membranes for implant technology to provide a TRUE-to-LIFE response for drug screening and cancer research. Perfectly suited for implantation, the modified Polyvinylidene Difluoride (mPVDF) hollow fiber membrane is biocompatible, resistant to cell adhesion, hydrophobic and resistant to a wide variety of organic solvents, including most aqueous acids and bases. Furthermore, these hollow fibers can be heat sealed and autoclaved without affecting the molecular weight cut off (500,000 Dalton MWCO) or changing the membrane performance.\u003c\/p\u003e\n\u003cp\u003eThe KrosFlo Implant Membranes has been shown to be biocompatible in various animal models for periods exceeding 14 days. Multiple cell lines have been grown both\u003cspan\u003e \u003c\/span\u003e\u003ci\u003ein vitro\u003c\/i\u003e\u003cspan\u003e \u003c\/span\u003eand\u003cspan\u003e \u003c\/span\u003e\u003ci\u003ein vivo\u003c\/i\u003e\u003cspan\u003e \u003c\/span\u003ewithin the KrosFlo Implant Membranes. Cell lines grown within KrosFlo Implant Membranes, which have been implanted into a host animal, are not subject to immunological attack by the host animal. KrosFlo Implant Membranes containing cancer cell lines have been implanted into mice and used to screen for compounds having anti cancer activity. Similarly, KrosFlo Implant Membranes containing HIV infected cell lines have been implanted into mice and used to screen for compounds having anti-HIV activity. Literature describing the implantation of KrosFlo Implant Membrane in these animal models is available at www.spectrumlabs.com.\u003c\/p\u003e\n\u003cp class=\"ul\"\u003e\u003cb\u003eEncapsulated cells can be:\u003c\/b\u003e\u003c\/p\u003e\n\u003cul class=\"compact\"\u003e\n\u003cli\u003eEstablished cancer cell lines\u003c\/li\u003e\n\u003cli\u003eVirus infected cells\u003c\/li\u003e\n\u003cli\u003eHematopoietic cells\u003c\/li\u003e\n\u003cli\u003eBacteria\u003c\/li\u003e\n\u003cli\u003eFungi\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"ul\"\u003e\u003cb\u003eKrosFlo Implant Membranes isolate:\u003c\/b\u003e\u003c\/p\u003e\n\u003cul class=\"compact\"\u003e\n\u003cli\u003eImmune systems cells\u003c\/li\u003e\n\u003cli\u003eViruses\u003c\/li\u003e\n\u003cli\u003eMycoplasma\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"ul\"\u003e\u003cb\u003eKrosFlo Implant Membranes have:\u003c\/b\u003e\u003c\/p\u003e\n\u003cul class=\"compact\"\u003e\n\u003cli\u003eBiocompatible inner and outer surface\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"ul\"\u003e\u003cb\u003eAdvantages over current xenographic model:\u003c\/b\u003e\u003c\/p\u003e\n\u003cul class=\"compact\"\u003e\n\u003cli\u003e10 day assay versus 60 day assay\u003c\/li\u003e\n\u003cli\u003eSmaller assay variability, fewer animals needed\u003c\/li\u003e\n\u003cli\u003eUses lesser amounts of test compounds\u003c\/li\u003e\n\u003cli\u003eMultiple cell lines can be tested simultaneously in same animal\u003c\/li\u003e\n\u003cli\u003eCompatible with different cell lines\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 class=\"SubHeader\"\u003eSpecifications:\u003c\/h2\u003e\n\u003ctable class=\"p_s\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd class=\"p_sl\"\u003ePackaging:\u003c\/td\u003e\n\u003ctd\u003eWet in DI water and autoclaved or Dry and not autoclaved\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"p_sl\"\u003eMaterial:\u003c\/td\u003e\n\u003ctd\u003ePVDF\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"p_sl\"\u003eInner Diameter:\u003c\/td\u003e\n\u003ctd\u003e1.0 mm\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"p_sl\"\u003eOuter Diameter:\u003c\/td\u003e\n\u003ctd\u003e1.2 mm\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"p_sl\"\u003eLength:\u003c\/td\u003e\n\u003ctd\u003e34 cm per fiber\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"p_sl\"\u003eQuantity:\u003c\/td\u003e\n\u003ctd\u003eThree fibers per package\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e","brand":"Repligen","offers":[{"title":"White \/ 500kD Wet","offer_id":31419938373705,"sku":"M138615","price":94.58,"currency_code":"EUR","in_stock":true},{"title":"White \/ 500kD Dry","offer_id":31419938439241,"sku":"S9320101","price":94.58,"currency_code":"EUR","in_stock":true},{"title":"Blue \/ 500kD Wet","offer_id":31419938537545,"sku":"M138616","price":94.58,"currency_code":"EUR","in_stock":true},{"title":"Blue \/ 500kD Dry","offer_id":31419938570313,"sku":"S9320102","price":94.58,"currency_code":"EUR","in_stock":true},{"title":"Yellow \/ 500kD Wet","offer_id":31419938635849,"sku":"M138617","price":94.58,"currency_code":"EUR","in_stock":true},{"title":"Green \/ 500kD Wet","offer_id":31419938701385,"sku":"M138618","price":94.58,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0272\/3574\/5865\/products\/Implants.jpg?v=1587737192","url":"https:\/\/repligen-eu-store.myshopify.com\/products\/krosfloimplantmembrane","provider":"Repligen EU Store","version":"1.0","type":"link"}